KORTUC Inc. has been conducting a collaborative research with Professor Mark De Ridder at UZ Brussel to investigate the KORTUC radiosensitizing mechanism of action.
New result from this research will be presented at annual meeting of ESTRO (European Society for Radiotherapy and Oncology) held in May 2023.
In this study, it was shown that the radiosensitizing effect of H2O2 under hypoxic conditions can be attributed to the inhibition of cellular respiration through a complex I (exist on the inner mitochondrial membrane) blockade, in addition to reoxygenating cells.
Further information can be found below:
ESTRO2023 WEB site : https://www.estro.org/Congresses/ESTRO-2023
KRC-01’s abstract : Abstract