Title
Tumour reoxygenation after intratumoural hydrogen peroxide (KORTUC) injection: a novel approach to enhance radiosensitivity
Authors
Samantha Nimalasena, John Yarnold, Navita Somaiah et al.
Summary
A pre-clinical study by the team at The Institute of Cancer Research (ICR), who is conducting the pivotal Phase 2 clinical trial of KORTUC (KRC-01) for breast cancer , was recently published in BJC Reports, a journal in the s Nature Portfolio.
The tumour reoxygenation is known as a key factor in overcoming radiation therapy resistance. This article demonstrates tumour reoxygenation by KORTUC in vitro/in vivo model, and shows its promising potential of KORTUC for the treatment of hypoxic tumors across various cancer types.
https://www.nature.com/articles/s44276-024-00098-y